BGG Life
The BGG Global Science & Business Journal · BGG全球科学与商业期刊
Vol. 1 · No. 1
June 2026
🔒 Internal Distribution Only · 仅限内部传阅
BGG Life May 2026 Cover — microalgae cultivation

来自海洋和初始的生命讯息
From Ocean to Evidence

Microalgae ingredients reach clinical and commercial maturity — BGG's Dream Team at Vitafoods Europe 2026, the AstaZine® VDT patent, and the geroscience wave reshaping human health nutrition.

Also in This Issue

Research
China NHC 2026 Sarcopenia Dietary Guideline — policy-backed signal for healthy aging nutrition
Research
CaAKG and cognitive aging: Brian Kennedy / NUS geroscience approach
BGG Business
BGG at Vitafoods Europe 2026: the Dream Team of ApplePhenon®, TheraPrimE® and AstaZine®
BGG Business
AstaZine® Patent No. 7832221: exclusive VDT vision health claim in Japan
People of BGG
Bharat Ramamoorthy takes charge at BGG Europe & International Division
Comment
生命始终的秘密——From Anti-Aging Claims to Biological-Age Evidence: A CEO Perspective on the "Life Clock" Era
Contents · 目录 — Vol. 1 · No. 1 · June 2026
S-01 · Editorial · 主编寄语
The Algae Moment Has Arrived — and a New Chapter for BGG's Global Marketing
藻类时代已来——BGG全球营销的新篇章
Kun Li
S-02 · Science Insight · 科技前沿
World's Highest Natural-Concentration EPA Algae Oil: Fermentalg's Omega Origins™ and the New Benchmark for Marine Omega-3 Ingredients
全球最高天然浓度EPA藻油:Fermentalg Omega Origins™与海洋Omega-3原料新标杆
S-02-01
Saskatoon Berries Demonstrate ACE Inhibition and Prebiotic Gut Microbiome Effects Surpassing Blueberries
萨斯卡通浆果展现超越蓝莓的ACE抑制与益生元肠道微生物效应
S-02-02
Rosemary–Curcumin–Piperine Phytochemical Combination Reduces Post-Exercise Muscle Damage Biomarkers in RCT
迷迭香-姜黄素-胡椒碱植物组合在RCT中显著降低运动后肌肉损伤生物标志物
S-02-03
Kaempferol and the Oxygen Efficiency Hypothesis: Otsuka Pharmaceutical's Zeroz
山奈酚与氧气效率假说:大塚制药Zeroz产品解析
S-02-04
Moderate-Dose Vitamin E Optimises Exercise-Induced Oxidative Stress Response: PGC-1α Expression Study
中等剂量维生素E优化运动诱发氧化应激反应:PGC-1α表达研究
S-02-05
China's 2026 Adult Sarcopenia Dietary Guideline: A Policy-Backed Market Signal for Healthy Aging Nutrition
中国2026年成人肌肉衰减综合征膳食指南:政策驱动的健康老龄化营养市场信号
S-02-06
Calcium Alpha-Ketoglutarate and the Geroscience Approach to Cognitive Aging: Brian Kennedy's NUS Research
钙α-酮戊二酸与老龄科学认知衰老研究路径:Brian Kennedy新加坡国立大学研究
S-02-07
S-03 · Market Watch · 市场观察
Japan · US · China · Global Market Intelligence Roundup
日本·美国·中国·全球市场情报汇总
S-03
S-04 · BGG Business · 商业动态
BGG at Vitafoods Europe 2026: The 'Dream Team' of ApplePhenon®, TheraPrimE® and AstaZine® Takes the Global Stage in Barcelona
BGG亮相2026欧洲营养食品展:ApplePhenon®、TheraPrimE®与AstaZine®"梦之队"登上巴塞罗那全球舞台
S-04-01
BGG Japan Granted Patent No. 7832221: AstaZine® VDT Vision Health Claim
BGG日本获得第7832221号专利:AstaZine® VDT视觉健康功能声称
S-04-02
BGG Japan March 2026 Customer Product Approvals
BGG日本2026年3月客户产品审批情况
S-04-03
S-05 · People of BGG · BGG人物
Bharat Ramamoorthy Takes Charge at BGG Europe and International Division
Bharat Ramamoorthy出任BGG欧洲及国际部门负责人
S-05-01
S-06 · World View · 全球声音
Bill Barclay and the Birth of the Microalgae Omega-3 Industry: GOED Lifetime Achievement Award, Singapore 2026
Bill Barclay与微藻Omega-3行业的诞生:2026年新加坡GOED终身成就奖
S-06-01
Euglena Acquires Kobelco Microalgae Assets: Building an Immunity Platform
优格力那收购神户制钢微藻资产:构建多元免疫平台
S-06-02
From Abandoned School to Luxury Amenity: Blue Scientific's Island Cosmetics
从废弃校舍到高端配套:Blue Scientific的岛屿美妆品牌
S-06-03
MartinBauer AnnurTriComplex: Non-Hormonal Hair Growth Targeting GLP-1 Side Effects
MartinBauer AnnurTriComplex:针对GLP-1副作用的非激素型生发原料
S-06-04
S-07 · Comment · Culture & Life · 文化生活
生命始终的秘密——从抗衰老宣称到生物年龄证据:CEO视角下的"生命时钟"时代
From Anti-Aging Claims to Biological-Age Evidence: A CEO Perspective on the "Life Clock" Era
S-07-04
Costco Protein Aisle, June 2026: Shelf Observation Report and Implications for BGG Ingredient Strategy
2026年6月Costco蛋白质货架观察报告及对BGG原料战略的启示
S-07-05
S-08 · From the Archive · 历史存档
风雨兼程三十年 · 寻草记
Thirty Years Through Wind and Rain · In Search of the Herb — Poem by Mr. Li 李春华, Founder & CEO, BGG Global
S-08-01
BGG全员专栏 · 样文:BGG与虾青素时代
BGG-Wide Column · Sample Article: BGG and the Astaxanthin Era
S-08-02

Editorial · 主编寄语

Editor-in-Chief · Monthly Opening
Kun Li · BGG Global CEO & Editor-in-Chief
🔒 Internal Only BGG Life Editorial May 2026

Every once in a while, an industry trend arrives not as a disruption, but as a confirmation — a quiet yet powerful validation of the choices, convictions, and long-term investments made years before. This May, as I look through the stories gathered in this issue of BGG Life, I feel that sense of confirmation with particular clarity.

Microalgae — the foundation upon which much of BGG's scientific heritage has been built — is no longer a niche conversation. At Vitafoods Europe in Barcelona this spring, the world's leading nutrition ingredient companies placed algae firmly at the center of innovation: Fermentalg introduced what may be one of the world's highest natural-concentration EPA oils; Euglena advanced its immunology platform through the acquisition of microalgae assets; even Honda — yes, the automotive company — is using algae to rethink the future of the protein supply chain. The direction of the industry has become unmistakable.

For BGG, this is not a moment to stand aside and observe. It is a moment to lead with confidence, discipline, and generosity of vision. Our AstaZine® has recently secured a landmark patent in Japan for its VDT vision health claim, demonstrating once again that clinical rigor, patient investment, and thoughtful patent strategy can create enduring competitive advantage. At Vitafoods, our team presented ApplePhenon®, TheraPrimE®, and AstaZine® as a compelling "Dream Team," telling a coherent clinical story around metabolic resilience, cognitive health, and the broader future of healthy aging.

Yet leadership in today's global market requires more than strong science alone. It requires the ability to translate science into trust, trust into value, and value into sustainable commercial relationships. This is why the establishment of BGG's Global Marketing Department marks an important milestone for the Group.

The creation of this department is not simply an organizational adjustment. It represents a new commitment to raising the quality of commerce across BGG Group. By building a stronger global marketing function, we are creating a shared platform for market insight, brand strategy, product storytelling, customer education, sales enablement, and cross-regional coordination. We are strengthening the bridge between research and market, between innovation and application, and between BGG's scientific capabilities and the real needs of customers around the world.

My hope is that the Global Marketing Department will help BGG move beyond fragmented commercial activities toward a higher standard of global commercial excellence. This means clearer positioning, more disciplined messaging, more consistent customer experience, faster response to market opportunities, and a stronger ability to convert our scientific assets into meaningful business growth. More importantly, it will help us build a more professional, more collaborative, and more future-oriented commercial culture within BGG Group.

This issue also touches on a subject closer to home. I drafted an article for our team's reflection — a structural analysis of single-decision-maker governance. For any founder-led organization, this is not necessarily comfortable reading. But it is necessary reading. As BGG continues to grow, as our markets multiply and our supply chains extend, the way we make decisions becomes not merely a matter of culture, but a strategic variable that will directly influence our long-term competitiveness.

BGG Life exists to ensure that everyone across our global organization is looking toward the same horizon. I hope this issue offers not only information, but also perspective — on where the science is moving, where the markets are heading, and how BGG can continue to elevate the quality of its commerce, its governance, and its global leadership.

As we enter this next stage, I believe the establishment of the Global Marketing Department will bring renewed energy, clearer direction, and higher standards to BGG Group. It is a hopeful step — not only toward stronger growth, but toward a more integrated, more professional, and more globally respected BGG.

每隔一段时间,行业都会迎来某种重要趋势。它并不一定以"颠覆者"的姿态出现,而更像是一种确认——对那些多年前便已悄然布局、坚定投入并持续深耕的战略选择,给予一种安静却有力的验证。今年五月,当我翻阅本期《BGG Life》所汇集的内容时,这种"被验证"的感受尤为清晰。

微藻——这一构筑BGG科学传承根基的重要领域——如今早已不再是小众话题。2026年春季于巴塞罗那举办的Vitafoods Europe展会上,全球领先的营养健康原料企业纷纷将微藻推向创新舞台的中央:Fermentalg推出了或许是全球天然浓度最高之一的EPA藻油产品;Euglena通过收购微藻相关资产,加速构建其免疫健康创新平台;甚至本田Honda——也正在借助微藻技术重新思考未来蛋白供应链的模式与可能性。行业发展的方向已经变得十分明确。

对于BGG而言,这并不是一个置身事外、静观其变的时刻,而是一个以信心、纪律与更开阔视野主动引领行业发展的时刻。我们的AstaZine®近期在日本成功获得针对VDT视觉健康功效的重要专利授权,再次证明:持续的临床研究投入、长期主义的科学积累,以及具有前瞻性的专利战略,终将沉淀为难以复制的竞争优势。在Vitafoods展会上,BGG团队将ApplePhenon®、TheraPrimE®与AstaZine®共同呈现为具有协同价值的"Dream Team",以系统化的临床科学逻辑,讲述关于代谢韧性、认知健康以及健康老龄化未来趋势的完整故事。

然而,在今天的全球市场中,真正的领导力并不仅仅来自强大的科学能力。它还要求我们能够将科学转化为信任,将信任转化为价值,并将价值转化为可持续的商业关系。正因为如此,BGG 全球市场部的建立,对于整个集团而言,是一个具有重要意义的里程碑。

全球市场部的设立,并不仅仅是一次组织架构上的调整。它代表着BGG对于提升集团整体商业质量的一项全新承诺。通过建立更强大的全球市场职能,我们正在为市场洞察、品牌战略、产品叙事、客户教育、销售赋能以及跨区域协同打造一个更加统一和专业的平台。

我期待全球市场部能够帮助BGG从相对分散的商业活动,迈向更高标准的全球商业卓越。这意味着更加清晰的市场定位,更加严谨的传播语言,更加一致的客户体验,更加快速的市场响应能力,以及更强的能力将我们的科学资产转化为真正有意义的商业增长。更重要的是,它将帮助BGG在集团内部逐步建立一种更加专业、更加协同、更加面向未来的商业文化。

本期内容同样聚焦一个更加贴近企业自身发展的重要议题。我为团队撰写了一篇关于"单一决策者治理模式"的结构性分析文章。随着BGG持续成长,市场版图不断扩展,全球供应链体系日趋复杂,"我们如何做出决策"已经不再只是企业文化层面的偏好选择,而正在成为影响长期竞争力的重要战略变量。

《BGG Life》的使命,是确保遍布全球各地的BGG团队成员能够共同眺望同一个未来方向。进入新的发展阶段,我相信全球市场部的建立,将为BGG Group带来新的能量、更清晰的方向和更高的标准。这是一个充满希望的开始——它不仅关乎更强劲的增长,也关乎一个更加整合、更加专业、并在全球范围内更受尊重的BGG。

Kun Li · Editor-in-Chief, BGG Life · CEO, BGG Global · 11 May 2026

Science Insight · 科技前沿

Research · News & Views · Science Analysis
Deputy Editors: 张扬 博士 · 丁立新 博士 · 关川 博士

World's Highest Natural-Concentration EPA Algae Oil: Fermentalg's Omega Origins™ and the New Benchmark for Marine Omega-3 Ingredients

全球最高天然浓度EPA藻油:Fermentalg Omega Origins™与海洋Omega-3原料新基准

🔒 Internal Microalgae EPA fermentation
Abstract · English摘要 · 中文
French biotechnology firm Fermentalg has launched Omega Origins™, an algae-derived omega-3 oil achieving 400 mg/g EPA at natural concentration without chemical processing. This represents a new benchmark for the marine omega-3 ingredient category and is being positioned as a direct competitor to high-concentration fish oil in cardiovascular and athletic recovery markets. 法国生物技术公司Fermentalg推出Omega Origins™,这是一种藻类来源的Omega-3油脂,在不经化学加工的前提下,天然浓度即可达到400 mg/g EPA。这一成果为海洋Omega-3原料品类树立了新标杆,并被定位为心血管健康及运动恢复市场中高浓度鱼油的直接竞争对手。
Breaking the Chemical Concentration Barrier突破化学浓缩壁垒
Conventional high-concentration omega-3 products have historically required ethyl esterification to achieve EPA concentrations above 300 mg per gram. Fermentalg's Omega Origins™ achieves its 400/200 EPA/DHA ratio directly from microalgae through proprietary precision fermentation, with total omega-3 content reaching 60% of the raw oil. This is a category first. 传统高浓度Omega-3产品历来需要乙酯化处理才能将EPA浓度提升至300 mg/g以上。Fermentalg的Omega Origins™通过专有精准发酵技术,直接从微藻中获得400/200的EPA/DHA比例,原油中Omega-3总含量达60%。这在品类中尚属首次。
Strategic Timing: Fish Oil Supply Pressure战略时机:鱼油供应压力
The launch coincides with significant upward price pressure on conventional fish oil, driven by reduced anchovy catch quotas and production volatility in South American fisheries. Fermentalg's large-scale fermentation capacity — anchored through its partnership with Huvepharma — positions Omega Origins™ as a supply-stable alternative. Per tonne of product produced, approximately 44 tonnes of deep-sea anchovies are protected from harvest. 此次上市恰逢传统鱼油价格承压显著上行,原因在于凤尾鱼捕捞配额削减及南美渔业生产波动。Fermentalg凭借与Huvepharma合作建立的大规模发酵产能,将Omega Origins™定位为供应稳定的替代选择。每生产一吨产品,约可保护44吨深海凤尾鱼免遭捕捞。
Key Takeaways · 核心要点
  • Omega Origins™ achieves 400 mg/g natural-concentration EPA — a category first, without chemical processing. / 品类首创,无需化学加工。
  • Fish oil supply constraints in 2026 are creating a structural commercial window for fermentation-derived algae alternatives. / 2026年鱼油供应收紧,为发酵来源藻油创造结构性商业窗口。
  • Product range (150/300, 100/500, 400/200 ratios) covers infant cognitive development through cardiovascular and athletic recovery. / 产品系列覆盖从婴幼儿认知发育到心血管健康及运动恢复的全场景定位。

Saskatoon Berries Demonstrate ACE Inhibition and Prebiotic Gut Microbiome Effects Surpassing Blueberries

沙果莓展现出超越蓝莓的ACE抑制活性与益生元样肠道菌群调节效应

🔒 Internal Saskatoon berry research
Abstract · English摘要 · 中文
A pre-clinical study in IJMS (April 2026) demonstrates that Amelanchier alnifolia (Saskatoon berry) extract produces measurable ACE inhibitory activity, endothelial function improvements, and prebiotic gut microbiome modulation. Antioxidant profile (quercetin, anthocyanins, chlorogenic acid) and mineral density exceed blueberries. The authors describe a 'gut-heart axis' mechanism — cardiovascular benefits may be partly mediated through improved gut microbiota composition. 2026年4月发表于IJMS的一项临床前研究显示,北美唐棣提取物具有可测量的ACE抑制活性、内皮功能改善效应及益生元样肠道菌群调节作用。其抗氧化物组成及矿物质密度均超过蓝莓。作者提出"肠-心轴"机制——心血管益处可能部分通过改善肠道菌群组成来介导。
Key Takeaways · 核心要点
  • ACE-inhibitory activity supports blood pressure and cardiovascular health formulation claims. / ACE抑制活性为血压调节和心血管健康配方声明提供支持。
  • Prebiotic gut microbiome effects (↑ Bifidobacterium) suggest a gut–heart axis mechanism. / 益生元样效应提示肠-心轴机制。
  • Higher iron, calcium, and dietary fibre vs blueberries enables differentiated whole-nutrition positioning. / 铁、钙和膳食纤维含量高于蓝莓,支持差异化全营养定位。

Rosemary–Curcumin–Piperine Phytochemical Combination Reduces Post-Exercise Muscle Damage Biomarkers in RCT

迷迭香-姜黄素-胡椒碱植化素组合在RCT中降低运动后肌肉损伤生物标志物

🔒 Internal Sports recovery formulation
Abstract · English摘要 · 中文
A randomised controlled trial in Nutrients (April 2026) demonstrates that a combination of rosemary extract (carnosic acid), curcumin, and piperine significantly reduces creatine kinase at 24 h and 48 h post-exercise, suppresses pro-inflammatory IL-6, and decreases DOMS versus placebo. This natural, multi-compound recovery formulation offers a clinically validated alternative to NSAIDs. The inclusion of piperine is mechanistically critical: it enhances curcumin bioavailability by up to 2,000% through inhibition of hepatic and intestinal glucuronidation. 发表于Nutrients(2026年4月)的一项随机对照试验表明,迷迭香提取物(鼠尾草酸)、姜黄素与胡椒碱的组合显著降低运动后24小时和48小时的肌酸激酶水平,抑制促炎因子IL-6,并减轻延迟性肌肉酸痛(DOMS)。这一天然多化合物恢复配方为NSAIDs提供了经临床验证的替代选择。胡椒碱可将姜黄素的生物利用度提升高达2,000%。
"As consumer concern about NSAID side effects grows, clinically validated natural recovery formulations represent a genuine category opportunity for premium sports nutrition brands."
Key Takeaways · 核心要点
  • Rosemary + curcumin + piperine combination reduces post-exercise CK and IL-6 versus placebo in a published RCT.
  • Piperine's bioavailability-enhancement role is critical: enables curcumin absorption at up to 20× its unenhanced baseline.
  • Natural muscle-recovery formulations are gaining clinical credibility as NSAID safety concerns drive consumer interest.

Kaempferol and the Oxygen Efficiency Hypothesis: Otsuka Pharmaceutical's Zeroz

山奈酚与氧气效率假说:大塚制药Zeroz产品解析

🔒 Internal Kaempferol ATP research
Analysis · English分析 · 中文
Otsuka Pharmaceutical's 'Zeroz' product is built around a deceptively simple question: why do high-altitude populations — living in low-oxygen environments — frequently demonstrate superior athletic performance? The research team screened 341 highland food ingredients for ATP production enhancement, then applied computational chemistry to analyse 12,168 compounds. Result: kaempferol, extracted from domestic wasabi leaf, emerged as the highest-activity compound. Human clinical trials confirmed increased physical activity levels, reduced resting heart rate, and improved sleep quality. 大塚制药旗下"Zeroz"产品的核心出发点是一个看似简单却意味深长的问题:为何长期生活在低氧高海拔环境中的人群往往表现出更优异的运动能力?研究团队对341种高原食材进行ATP促进效果筛选,并运用计算化学分析了12,168种化合物。结果显示:从国产山葵叶中提取的山奈酚是活性最高的化合物。人体临床试验进一步证实,山奈酚可提高身体活动水平、降低静息心率并改善睡眠质量。
Key Takeaways · 核心要点
  • Kaempferol identified via screen of 12,168 compounds as top ATP-efficiency activator. / 12,168种化合物筛选中确认为最强ATP效率激活剂。
  • RCT shows ↑ activity, ↓ heart rate, ↑ sleep quality — multi-benefit mitochondrial profile.
  • Kaempferol approaching mainstream Japan market adoption across categories. / 正逐步在日本市场多品类主流渠道中获得采用。

Moderate-Dose Vitamin E Optimises Exercise-Induced Oxidative Stress Response: PGC-1α Expression Study

适量维生素E优化运动诱导氧化应激反应:PGC-1α表达研究

🔒 Internal Vitamin E exercise study
Analysis · English分析 · 中文
Research led by Rina Suzuki (Kyorin University) demonstrates that the relationship between vitamin E supplementation and exercise-induced oxidative stress follows a non-linear dose–response pattern. Moderate dosing outperforms both lower and higher doses in suppressing inflammatory response and promoting exercise adaptation. The moderate-dose group showed the strongest PGC-1α upregulation — the master regulator of mitochondrial biogenesis. High-dose supplementation did not outperform moderate dosing, consistent with the principle that excess antioxidants can blunt the hormetic stress response that makes exercise beneficial. 铃木利奈(杏林大学)主导的研究表明,维生素E补充量与运动诱导氧化应激之间呈非线性剂量-反应关系。适量补充在抑制炎症反应和促进运动适应方面优于低剂量和高剂量。适量组表现出最强的PGC-1α上调效应——PGC-1α是线粒体生物合成的主调控因子。高剂量补充效果并不优于适量组,与"过量抗氧化剂可能减弱运动获益所依赖的兴奋效应"这一原则相吻合。
Key Takeaways · 核心要点
  • Moderate-dose vitamin E maximises anti-inflammatory effect and PGC-1α expression during exercise.
  • High-dose supplementation shows diminishing returns — 'more is not better' principle confirmed. / "多即是好"原则被证伪。
  • Optimal dose positioning, not maximum dose, is the key formulation differentiator. / 最优剂量定位是配方差异化的关键。

China's 2026 Adult Sarcopenia Dietary Guideline: A Policy-Backed Market Signal for Healthy Aging Nutrition

中国2026年成人肌少症膳食指南:健康老龄化营养的政策支撑市场信号

🔒 Internal China sarcopenia guideline healthy aging
Abstract · English摘要 · 中文
China's National Health Commission issued the Adult Sarcopenia Dietary Guideline (2026 Edition) on 3 April 2026, establishing sarcopenia — progressive loss of skeletal muscle mass, strength, and function — as a national public health priority. The guideline's seven core principles create a policy-backed framework for nutrition supplementation, resistance training, and targeted functional ingredient use. This is the strongest Chinese regulatory signal to date for BGG's healthy aging and anti-inflammatory nutrition strategy. 中国国家卫生健康委于2026年4月3日发布《成人肌少症膳食指南(2026年版)》,将肌少症(骨骼肌质量、力量和功能的进行性丧失)列为国家公共卫生优先事项。该指南的七项核心原则为营养补充、抗阻训练和靶向功能性原料的使用提供了政策支撑框架。这是迄今为止对BGG健康老龄化和抗炎营养战略最强烈的中国法规信号。
Why This Matters: China's Demographic Imperative重要意义:中国人口老龄化的迫切需求
With over 300 million people aged 60 and above, China's aging population is the largest in the world in absolute terms. Sarcopenia affects an estimated 10–27% of community-dwelling older adults globally, with higher rates in Asian populations. The NHC's decision to issue this guideline signals a coordinated nutritional strategy for age-related chronic conditions that will define the Chinese functional food and supplement market for the next two decades. 中国60岁以上人口超过3亿,是全球老龄人口最多的国家。全球社区老年人中肌少症患病率估计为10%–27%,亚洲人群比例更高。国家卫健委此次发布标志着针对年龄相关慢性病的协调营养战略正在形成,这将在未来二十年重塑中国功能食品与保健品市场格局。
Seven Core Principles · 七项核心原则
  • 1. Adequate high-quality protein distributed across meals · 充足优质蛋白质,分餐摄入
  • 2. Higher overall nutrient density · 提高整体营养密度
  • 3. Targeted nutrition supplementation when dietary intake is insufficient · 膳食摄入不足时进行靶向营养补充
  • 4. Diversified physical activity with emphasis on resistance training · 多样化体力活动,重点加强抗阻训练
  • 5. Scientific use of food-medicine substances(药食同源)based on individual needs
  • 6. Active management of underlying disease · 积极管理基础疾病
  • 7. Early screening, diagnosis, and intervention · 早筛查、早诊断、早干预
BGG Strategic Relevance · BGG战略关联性
AstaZine® astaxanthin's anti-inflammatory and mitochondrial function support mechanisms are directly relevant to sarcopenia's inflammatory aetiology. ApplePhenon®'s metabolic health positioning aligns with the guideline's emphasis on nutrient density. TheraPrimE® tocotrienols address mitochondrial efficiency and oxidative stress — both implicated in age-related muscle function decline. The 'food-medicine substances' provision also opens a regulatory pathway for BGG's licorice extract portfolio.

AstaZine®虾青素的抗炎和线粒体功能支持机制与肌少症的炎症病因直接相关。ApplePhenon®的代谢健康定位与指南强调的营养密度高度吻合。TheraPrimE®生育三烯酚针对线粒体效率和氧化应激。"药食同源"条款也为BGG甘草提取物产品组合开辟了法规路径。
"Sarcopenia policy codification in China means the claim pathway is now clearer than the evidence pathway — an unusual and commercially significant inversion."
Key Takeaways · 核心要点
  • China NHC has officially classified adult sarcopenia as a public health priority with a national dietary guideline including supplementation principles. / 中国国家卫健委已正式将成人肌少症列为公共卫生优先事项。
  • Seven core principles include targeted nutrition supplementation, high-quality protein, and resistance exercise — all directly relevant to BGG's healthy aging portfolio.
  • Policy codification creates claim-pathway clarity for functional ingredients targeting muscle mass, strength, and energy in older adults in China. / 政策化为功能性原料提供了清晰的声明路径。

Calcium Alpha-Ketoglutarate and the Geroscience Approach to Cognitive Aging: Brian Kennedy's NUS Research

α-酮戊二酸钙与认知老龄化的老年科学研究路径:Kennedy教授新加坡国立大学研究

🔒 Internal Geroscience cognitive aging research
Abstract · English摘要 · 中文
Research from Prof. Brian Kennedy's group at NUS Medicine examines calcium alpha-ketoglutarate (CaAKG) — a naturally occurring metabolite whose tissue levels decline with age — in the context of Alzheimer's-related brain and memory dysfunction. The work extends the geroscience principle that interventions targeting the biology of aging upstream may address multiple age-related conditions simultaneously, including cognitive decline. 新加坡国立大学Brian Kennedy教授团队的研究以α-酮戊二酸钙(CaAKG)——一种随年龄增长组织水平下降的天然代谢物——为研究对象,探讨其在阿尔茨海默病相关脑功能和记忆障碍中的作用。该研究延伸了老年科学的核心原理:针对衰老上游生物学的干预措施或可同时应对包括认知衰退在内的多种年龄相关疾病。
The Geroscience Hypothesis老年科学假说
The geroscience hypothesis holds that biological aging is a root cause — not merely a risk factor — of most chronic age-related diseases. Kennedy's CaAKG work applies this logic specifically to synaptic plasticity and memory function: if age-related metabolic decline drives neural communication breakdown, then restoring the metabolite profile of younger tissue may preserve or recover cognitive function. 老年科学假说认为,生物衰老是大多数慢性年龄相关疾病的根本原因,而非仅仅是风险因素。Kennedy的CaAKG研究将这一逻辑具体应用于突触可塑性和记忆功能:若年龄相关代谢衰退导致神经通讯障碍,则恢复年轻组织的代谢物图谱或可保护甚至恢复认知功能。
Relevance to BGG's Cognitive Health Strategy与BGG认知健康战略的关联性
BGG's TheraPrimE® tocotrienol complex and AstaZine® astaxanthin both operate through mechanisms — mitochondrial function support, neuroinflammation reduction, oxidative stress mitigation — that are directly implicated in the geroscience model of cognitive aging. As clinical research in this space accelerates, BGG is well-positioned to leverage its ingredient evidence base in healthy cognitive aging claims. BGG的TheraPrimE®生育三烯酚复合物和AstaZine®虾青素均通过线粒体功能支持、神经炎症减轻、氧化应激缓解等机制发挥作用——这些机制直接参与认知老龄化的老年科学模型。随着该领域临床研究加速推进,BGG已具备充分条件,凭借原料证据基础在健康认知老龄化声明中取得先机。
Key Takeaways · 核心要点
  • CaAKG is a naturally occurring metabolite that declines with age and may support synaptic plasticity and memory in aging brain models. / CaAKG在老龄化脑模型中可能支持突触可塑性和记忆功能。
  • The research exemplifies geroscience translation: upstream aging-biology interventions targeting downstream cognitive outcomes. / 体现了老年科学的转化逻辑。
  • BGG relevance: TheraPrimE® and AstaZine® operate through mechanisms directly implicated in the geroscience model of cognitive aging.

Market Watch · 市场观察

Regulatory · Industry · Investment Intelligence
Market Watch May 2026 🔒 Internal Only
News · US Congress

Congress Advances Federal Supplement Regulatory Uniformity Act (H.R. 7366)

Republican Congressman Nick Langworthy's Dietary Supplement Regulatory Uniformity Act (H.R. 7366) has cleared a House Energy and Commerce Committee health subcommittee hearing (April 2026). The bill would establish FDA as the sole scientific regulatory authority for dietary supplements via federal preemption, prohibiting states from imposing additional requirements. CRN, NPA, and CHPA have expressed strong support.

BGG relevance: If enacted, this structurally favours ingredient companies with robust clinical evidence — science quality becomes the primary claim-eligibility filter. BGG's clinical evidence portfolio is a direct competitive asset under this scenario.

Source: NutraIngredients / BGGNA Market Intelligence · May 2026
Regulation · Japan

Japan Bans CBN Under Pharmaceutical Law, Effective 1 June 2026

Japan's MHLW has added cannabinol (CBN) to the list of designated substances under the Pharmaceutical and Medical Device Act. The ordinance (18 March 2026) prohibits manufacture, importation, sale, and use of CBN for all non-medical purposes from 1 June 2026. The CBN case demonstrates MHLW's readiness to act within 18 months of adverse-event confirmation — a timeline that should inform risk-management strategies for all novel ingredient categories in Japan.

Source: Asahi Shimbun / BGG Japan Monthly Report · March 2026

BGG Business · 商业动态

BGG Global · Commercial Reports · Patent Updates

BGG at Vitafoods Europe 2026: The 'Dream Team' of ApplePhenon®, TheraPrimE® and AstaZine® Takes the Global Stage in Barcelona

🔒 Internal Japan product approvals
Abstract
BGG presented the 'Dream Team' — ApplePhenon®, TheraPrimE®, and AstaZine® — as a coherent, clinically grounded response to three commercially significant health challenges: metabolic resilience, cognitive function, and sleep quality. Dr. Ding Lixin's keynote presentation and live format demonstrations drove significant post-show lead pipeline including a Nestlé Waters R&D discussion.

This May, BGG's Western Division team took center stage at Vitafoods Europe in Barcelona, Spain — the premier event for the global nutraceutical and functional food industry. The energy was palpable as our team connected with some of the world's biggest consumer brands, showcasing how BGG is driving innovation across the industry's most demanding sectors.

The "Dream Team" Meeting Top Consumer Trends

The team's showcase focused heavily on BGG's premier portfolio, a "Dream Team" of natural ingredient solutions perfectly aligned with today's top consumer health trends:

· ApplePhenon®: Addressing the massive demand for natural weight management solutions.
· TheraPrimE®: Leading the charge in cognitive health and mental clarity.
· AstaZine® Natural Astaxanthin: Supporting interconnected synergies within the body to promote positive aging.

These targeted solutions sparked incredible engagement. Not only is the Western team currently following up on a significant wave of post-show leads, but they also seamlessly passed regional contacts over to our teams in Asia — delivering a truly global, collaborative showcase of BGG's unified capabilities.

Japan product approvals Japan product approvals

Thought Leadership & Media in the Spotlight

Our impact stretched far beyond the sales booth, making waves in both live presentations and industry media. Lixin Ding and Tammi Higgins championed BGG's thought leadership throughout the event. Together, they participated in multiple media interviews with top industry publications, including a featured interview with Nutritional Outlook, which highlighted BGG's clinically studied solutions.

Metabolic Resilience Presentation → Nestlé Waters Discussion

In a 30-minute feature presentation, Lixin broke down shifting consumer demands, how BGG's flagship ingredients meet those needs, and the clinical proof of performance behind them. The impact was immediate: right after the presentation, the R&D decision-maker for Nestlé Waters walked straight to the BGG booth to initiate a highly promising partnership discussion — one of the most significant commercial outcomes of any single BGG conference appearance to date.

Japan product approvals Japan product approvals

The Weight Management Tour

BGG was also selected as a featured stop on Vitafoods' curated Weight Management Tour. Lixin addressed the tour group on the science-backed benefits of ApplePhenon®. Visitors experienced the ingredient firsthand through refreshing carbonated powder beverage tasting demos — directly addressing the persistent formulator objection that high-activity ingredients cannot coexist with compelling taste.

Vitafoods Europe 2026 was a resounding success. Kudos to everyone involved for representing BGG so powerfully on the world stage!

Key Takeaways · 核心要点
  • Dream Team (ApplePhenon® + TheraPrimE® + AstaZine®) presented as clinically integrated multi-target combination at Vitafoods Europe 2026.
  • Direct post-presentation interest from a Nestlé Waters R&D decision-maker illustrates how clinical credibility translates into concrete commercial conversations.
  • Seamless handoff of European leads to BGG Asia teams demonstrates the company's growing capacity to operate as a unified global sales organisation.

BGG Japan Granted Patent No. 7832221: AstaZine® VDT Vision Health Claim

🔒 Internal AstaZine VDT patent Japan

BGG Japan has been granted Patent No. 7832221 in Japan, covering use of AstaZine® for 'suppressing vision deterioration after VDT (Visual Display Terminal) work in individuals aged 40 and above.' The patent creates exclusive claim rights for a highly specific, commercially valuable health endpoint.

Only AstaZine®-containing products may now carry the functional food claim for vision maintenance in middle-aged and older adults during computer and smartphone use — a legal protection that cannot be replicated by competing astaxanthin suppliers.

Key Takeaways · 核心要点
  • Patent No. 7832221: exclusive rights to VDT vision health claim for AstaZine® in Japan.
  • Claim is legally protected — competing suppliers cannot replicate without matching the evidence base.
  • Adds to portfolio of distinct, patent-backed AstaZine® claims across eye, skin, and cognitive health.

BGG Japan March 2026 Customer Product Approvals

🔒 Internal Only — Customer Commercial Information Japan product approvals
Editorial Note
Customer product approval details for March 2026 are confirmed for internal distribution to this mailing list. Clinical trial progress data (source report p.12) was image-based and could not be extracted; the BGG Japan regional team has been asked to provide this data in text format for the June 2026 issue.

People of BGG · BGG人物

Profiles · Correspondence · Voices from across BGG

Bharat Ramamoorthy Takes Charge at BGG Europe and International Division

Bharat Ramamoorthy BGG Europe
Abstract
BGG has appointed Bharadhwaj 'Bharat' Ramamoorthy as CEO of BGG Europe and head of the International Division, succeeding Jürgen Nelis who transitions to Chairman of BGG Europe's Board. The appointment strengthens BGG's international management structure at a moment of strong commercial momentum.

A Transition of Leadership, Not of Direction

Jürgen Nelis, who built BGG's European operations through a sustained period of scientific credibility and commercial growth, transitions to Chairman of the BGG Europe Board. The structure preserves institutional knowledge while creating executive space for new leadership energy — a model that reflects BGG's preference for deliberate succession over abrupt change.

The Portfolio Bharat Inherits

Founded in 1995, BGG has built its global reputation around natural astaxanthin and microalgae-derived solutions. The current portfolio — AstaZine® (natural astaxanthin), TheraPrimE® (tocotrienols), ThinOgen® (fucoxanthin), ApplePhenon® (apple polyphenols), Vitosa® (stevia), and licorice extracts — serves dietary supplement, pharmaceutical, cosmetic, and functional food customers globally.

Bharat inherits this portfolio at an historically strong moment: the May 2026 AstaZine® VDT patent in Japan, the Dream Team's Vitafoods Europe showcase, and a post-show lead pipeline that represents some of the strongest near-term commercial signals in BGG's recent history.

Context: Three Simultaneous Dynamics

Bharat's mandate will play out against three intersecting trends: the maturation of the global supplement regulatory environment (H.R. 7366 in the US; CRN Japan 9th Edition), the emergence of GLP-1 companion nutrition and longevity as the dominant commercial theme in functional ingredients, and intensifying competition in the premium natural ingredient space where clinical evidence has become the primary differentiator.

"The consolidation of European and international leadership under a single executive is a structural statement — BGG is building for the next phase of global growth."
Key Takeaways · 核心要点
  • Bharat Ramamoorthy appointed CEO, BGG Europe and head of International Division, effective May 2026.
  • Jürgen Nelis transitions to Board Chairman — strategic continuity preserved alongside new executive leadership.
  • BGG's international portfolio enters this phase with strong clinical, patent, and commercial momentum.

World View · 全球声音

Global Voices · Industry Profiles · International Intelligence
🔒 Internal World View May 2026
Industry Profile

Bill Barclay and the Birth of the Microalgae Omega-3 Industry: GOED Lifetime Achievement Award, Singapore 2026

At the 2026 GOED Exchange in Singapore, Dr. Bill Barclay received the GOED Lifetime Achievement Award — recognition for a career that essentially created the commercial microalgae omega-3 industry. Barclay's foundational insight was that Schizochytrium — a marine microalgae — could produce DHA in commercially meaningful quantities through closed fermentation. This decision, made in the late 1980s, defined the entire subsequent architecture of the microalgae omega-3 industry.

Barclay founded OmegaTech Inc. in Colorado in 1987. The company partnered with Kelco/Merck for fermentation scale-up and regulatory approval, was acquired by Martek Inc., and eventually became part of today's dsm-firmenich.

"He didn't just develop an ingredient. He built a category — and the whole industry is still living inside the infrastructure he designed."

Barclay's journey is worth reading carefully in May 2026 — when Fermentalg is launching a world-first EPA algae oil, Honda is commercialising microalgae protein, and Euglena is acquiring biotech assets. The convergence echoes the early 1990s, when multiple actors simultaneously recognised that microalgae's potential was real but required new infrastructure to unlock.

Source: NutraIngredients / GOED Exchange, Singapore · April 2026
Acquisition

Euglena Acquires Kobelco Microalgae Assets: Building an Immunity Platform

Euglena Co. has completed acquisition of Kobelco Eco-Solutions' microalgae business, including Golden Euglena (EOD-1) production assets and the Micarea supplement brand. EOD-1's value centres on paramylon — a β-1,3-glucan polysaccharide with documented dual action on innate and adaptive immunity. The acquisition signals Euglena's intent to become a multi-ingredient immunity platform company rather than a single-ingredient specialty player.

Source: NutraIngredients · May 2026
Innovation · Japan

From Abandoned School to Luxury Amenity: Blue Scientific's Island Cosmetics

Blue Scientific Shinkamigoto (Nagasaki) operates its microalgae R&D facility in a former junior high school and has built a fucoxanthin-based organic cosmetics brand that sold over 10,000 units within two years of launch. From March 2026, its products are official amenities at GOTO RETREAT ray, a luxury island hotel. Fucoxanthin's anti-oxidative and anti-inflammatory properties are attracting increasing cosmetic formulator interest.

Source: Nagasaki ITV / BGG Japan Monthly Report · March 2026
Ingredient Launch · Vitafoods

MartinBauer AnnurTriComplex: Non-Hormonal Hair Growth Targeting GLP-1 Side Effects

MartinBauer Nutraceuticals launched AnnurTriComplex at Vitafoods Europe 2026 — a Procyanidin B2-rich Annurca apple polyphenol extract positioned for non-hormonal hair growth support. Key differentiator: mechanism bypasses DHT-inhibition pathways, operating instead through nutritional metabolism and follicle-cycle support. A 60-day RCT (250 subjects) showed significant hair growth increase vs. control at 400 mg twice daily. Explicit positioning: supporting patients experiencing hair loss as a GLP-1 receptor agonist side effect.

Source: NutraIngredients / Vitafoods Europe 2026

Comment · Culture & Life · 文化生活

Analysis · Perspective · Culture

从抗衰老宣称到生物年龄证据:CEO视角下的"生命时钟"时代

From Anti-Aging Claims to Biological-Age Evidence: A CEO Perspective on the "Life Clock" Era

🔒 Internal Only
Abstract
As biological-age "life clock" science matures, the anti-aging nutrition industry must move from inspirational language to measurable biology. BGG's portfolio — natural astaxanthin, fucoxanthin, tocotrienols, apple polyphenols, licorice actives — is already operating in the pathways these clocks measure. The strategic imperative is to organise those strengths under a rigorous scientific framework of biological resilience, rational formulation, and responsible human evidence.
BGG at Vitafoods Europe 2026 Barcelona

多年来,抗衰老行业一直使用相对宽泛的语言:活力、年轻态、能量、由内而外的美丽、健康老龄化和长寿。这些概念具有吸引力,在很多情况下也真实反映了消费者的需求。但随着科学的发展,行业本身也必须进一步成熟。抗衰老的下一阶段,将不再只由鼓舞人心的语言来定义,而将由可衡量的生物学变化来定义。

For many years, the anti-aging industry has spoken in broad language: vitality, youthfulness, energy, beauty from within, healthy aging, and longevity. These concepts are attractive, and in many cases they reflect genuine consumer needs. But as science advances, the industry must also mature. The next stage of anti-aging will not be defined only by inspirational language. It will be defined by measurable biological change.

这正是由 Brian Kennedy 博士及其合作者等衰老研究领域专家推动的"生命时钟"概念,对我们这个行业具有重要意义的原因。其核心思想简单而有力:实际年龄告诉我们一个人已经生活了多少年,而生物年龄可能更能说明身体功能状态如何、身体仍保有多少韧性,以及其向年龄相关衰退发展的速度。

This is why the emerging "life clock" concept, advanced through the work of leading aging researchers such as Dr. Brian Kennedy and his collaborators, is important for our industry. The central idea is simple but powerful: chronological age tells us how many years a person has lived, but biological age may tell us more about how well the body is functioning, how resilient it remains, and how quickly it is moving toward age-related decline.

在这一框架下,衰老不只是身份证或护照上的数字。它是一个可以被衡量的生物学过程。人体的"时钟"可能受到炎症、代谢功能障碍、氧化应激、血管健康、器官功能、免疫韧性、生活方式、饮食、环境,以及有针对性的营养干预等因素的影响而加快或减缓。对于处在抗衰老与健康寿命赛道的企业而言,这将从根本上改变行业对话的方式。

In this framework, aging is not merely a number on a passport. It is a measurable biological process. The body's "clock" can be accelerated or slowed by inflammation, metabolic dysfunction, oxidative stress, vascular health, organ function, immune resilience, lifestyle, diet, environment, and potentially targeted nutritional interventions. For companies operating in the anti-aging and health-span sector, this changes the conversation fundamentally.

对于 BGG 而言,这一理论与我们如何思考天然成分、微藻、植物提取物以及循证营养的未来高度相关。

At BGG, this is highly relevant to how we think about the future of natural ingredients, microalgae, botanical extracts, and evidence-based nutrition.

从实际年龄到生物功能 · The Shift from Chronological Age to Biological Function

传统抗衰老市场通常关注可见或主观感知的结果,例如更年轻的皮肤、更充沛的精力、更好的睡眠,或整体活力的提升。这些结果当然重要,但并不完整。更深层的问题是:一种干预是否能够在细胞、代谢、炎症、血管和系统层面支持人体韧性?

The traditional anti-aging market often focuses on visible or subjective outcomes: younger-looking skin, more energy, better sleep, or improved vitality. These outcomes matter, but they are incomplete. The deeper question is whether an intervention can support the body's resilience at the cellular, metabolic, inflammatory, vascular, and systemic levels.

衰老时钟研究提示我们,真正有价值的生物年龄工具不应只是估算一个人"看起来"在生物学上有多老。它们还应能够预测有意义的健康结果,包括功能下降和死亡风险。这一区别非常重要。一个只是模仿实际年龄的时钟,实际应用价值有限。而一个能够反映生物韧性、炎症状态、代谢状态和器官功能的时钟,则可能成为指导预防性健康策略的重要工具。

Aging-clock research suggests that the most useful biological-age tools should not simply estimate how old a person looks biologically. They should predict meaningful health outcomes, including functional decline and mortality risk. This is an important distinction. A clock that only mimics chronological age has limited practical value. A clock that reflects biological resilience, inflammation, metabolic status, and organ function may become a practical tool for guiding preventive health strategies.

这为营养和膳食补充剂行业提出了新的标准。未来的行业发展将不再仅由"抗衰老"这一营销词汇驱动,而将由企业是否能够把具体成分和配方,与健康老龄化相关的可衡量生物学通路连接起来所决定。

This creates a new standard for the nutrition and supplement industry. The future will not be driven only by "anti-aging" as a marketing phrase. It will be driven by the ability to connect specific ingredients and formulations with measurable biological pathways related to healthy aging.

为什么这对 BGG 重要 · Why This Matters for BGG

BGG 长期专注于与健康老龄化高度相关的天然化合物,包括来自微藻的天然虾青素、岩藻黄质、生育三烯酚、苹果多酚、甘草来源活性物、浆果提取物以及其他植物创新成分。许多此类成分传统上被定位于抗氧化保护、抗炎支持、代谢健康、循环支持、运动恢复和细胞保护等领域。

BGG has long focused on natural compounds with strong relevance to healthy aging: natural astaxanthin from microalgae, fucoxanthin, tocotrienols, apple polyphenols, licorice-derived actives, berry extracts, and other botanical innovations. Many of these ingredients are traditionally positioned around antioxidant protection, anti-inflammatory support, metabolic health, circulation, sports recovery, and cellular protection.

生命时钟理论为我们提供了一种更整合的方式来理解这些益处。

The life-clock theory gives us a more integrated way to understand these benefits.

例如,虾青素不应只被看作一种强抗氧化剂。它的战略意义可能在于支持多个与衰老相关的系统,包括氧化平衡、炎症调节、线粒体应激反应、细胞膜稳定性、微血管循环、肌肉恢复、皮肤韧性,以及更广泛的健康寿命功能。同样,岩藻黄质也不应只被看作一种体重管理成分,而应被评估为与代谢灵活性、脂质代谢和炎症相关衰老通路有关的活性物。

For example, astaxanthin should not be viewed only as a strong antioxidant. Its strategic relevance may lie in how it supports multiple aging-related systems: oxidative balance, inflammatory regulation, mitochondrial stress response, cell membrane stability, microvascular circulation, muscle recovery, skin resilience, and possibly broader health-span functions. Similarly, fucoxanthin may be evaluated not only as a weight-management ingredient, but as a compound connected to metabolic flexibility, lipid metabolism, and inflammation-related aging pathways.

这正是 BGG 需要推动的思维方式:不是单一功效宣称式的营销,而是系统层面的生物学定位。

This is the type of thinking BGG must advance: not single-claim marketing, but system-level biological positioning.

抗衰老的新语言:韧性,而非永生 · The New Language of Anti-Aging: Resilience, Not Immortality

膳食补充剂行业必须保持谨慎。抗衰老不应被表述为逆转年龄、治疗疾病或不现实地延长寿命的承诺。负责任的企业应避免夸大性宣称。

The supplement industry must be careful. Anti-aging should not be communicated as a promise to reverse age, cure disease, or extend life in an unrealistic way. Responsible companies should avoid exaggerated claims.

一种更科学、更可信的语言,是生物韧性。衰老与韧性下降密切相关:身体从压力、炎症、代谢失衡、免疫挑战、氧化压力和组织损伤中恢复的能力逐渐降低。因此,营养干预应被评估为是否能够帮助维持或改善支持人体韧性的系统。

A more scientific and credible language is biological resilience. Aging is associated with declining resilience: the body becomes less able to recover from stress, inflammation, metabolic imbalance, immune challenge, oxidative pressure, and tissue damage. Nutritional interventions should therefore be evaluated by whether they help maintain or improve the systems that support resilience.

这正是 BGG 可以建立稳健且负责任定位的地方。我们的使命不应是宣称天然成分可以"阻止衰老"。相反,我们的使命应是开发和供应高质量成分,以支持与健康老龄化相关的生物系统。这些系统包括:氧化应激防御、炎症平衡、细胞膜保护、线粒体与能量代谢、微血管循环、皮肤与眼部健康、肌肉恢复与体能表现、代谢健康,以及整体功能活力。这些领域并非彼此孤立。它们是相互关联的生物学维度。生命时钟框架有助于将它们整合在一起。

This is where BGG can build a strong and responsible position. Our mission should not be to claim that natural ingredients can "stop aging." Instead, our mission should be to develop and supply high-quality ingredients that support the biological systems associated with healthy aging — oxidative stress defense, inflammatory balance, cell membrane protection, mitochondrial and energy metabolism, microvascular circulation, skin and eye health, muscle recovery and physical performance, metabolic health, and overall functional vitality. These areas are not isolated. They are interconnected biological domains. The life-clock framework helps bring them together.

从成分到证据平台 · From Ingredients to Evidence Platforms

衰老时钟科学带来的一个重要启示是,膳食补充剂行业需要更好的研究设计。传统人体研究通常依赖相对狭窄的终点指标。尽管这些指标仍然重要,但我们也应考虑更广泛的生物年龄和健康寿命标志物。

One of the most important implications of aging-clock science is that the supplement industry needs better study designs. Traditional human studies often rely on narrow endpoints. While those endpoints remain important, we should also consider broader biological-age and health-span markers.

对于 BGG 而言,这意味着未来创新应朝三个方向发展。

For BGG, this means future innovation should move in three directions.

第一,我们应将核心成分与公认的衰老机制连接起来。对于虾青素,这包括氧化应激、炎症、线粒体应激、脂质氧化、细胞膜保护和血管功能。对于岩藻黄质,这包括代谢调节、脂质代谢和体重管理相关通路。对于生育三烯酚和植物多酚,这包括抗氧化网络、炎症信号和心血管代谢支持。

First, we should connect our core ingredients to recognized mechanisms of aging. For astaxanthin: oxidative stress, inflammation, mitochondrial stress, lipid oxidation, membrane protection, and vascular function. For fucoxanthin: metabolic regulation, lipid metabolism, and weight-management-related pathways. For tocotrienols and botanical polyphenols: antioxidant networks, inflammatory signaling, and cardiometabolic support.

第二,我们应支持更多人体证据。行业越来越需要将传统结局指标与现代生物标志物结合起来的临床研究。这可能包括炎症指标、代谢指标、血管指标、体能表现指标、皮肤生物标志物,以及在适当情况下使用生物年龄工具。

Second, we should support more human evidence. The industry increasingly needs clinical studies that combine conventional outcomes with modern biomarkers — inflammatory markers, metabolic markers, vascular markers, physical-performance measures, skin biomarkers, and, when appropriate, biological-age tools.

第三,我们应走向更有逻辑的配方设计。抗衰老的未来不太可能仅建立在单一成分之上,而将建立在能够支持多个衰老相关通路的理性组合之上。例如,一个健康老龄化配方可以结合微藻来源抗氧化成分、代谢支持型植物活性物、血管支持成分,以及支持线粒体功能和恢复的营养素。

Third, we should move toward formulation logic. The future of anti-aging will be built on rational combinations that support multiple aging-related pathways — microalgae-derived antioxidants, metabolic-support botanicals, vascular-support actives, and nutrients that support mitochondrial function and recovery.

行业机会:可衡量的健康老龄化 · The Industry Opportunity: Measurable Healthy Aging

消费者正在变得更加成熟。他们不再满足于模糊的宣称。他们希望了解产品如何发挥作用、有哪些证据支持,以及其益处是否可以被衡量。与此同时,全球医疗健康体系也正在从疾病治疗转向预防、早期干预和健康寿命延长。

Consumers are becoming more educated. They are no longer satisfied with vague claims. They want to understand how products work, what evidence supports them, and whether the benefits are measurable. At the same time, healthcare systems around the world are shifting from disease treatment to prevention, early intervention, and health-span extension.

BGG 不应只在成本、供应能力或原料规格上竞争。这些当然必要,但并不足够。我们还应在科学解读、应用创新、临床相关性和长期信任上竞争。生命时钟理论可以帮助 BGG 建立更先进的抗衰老平台,将成分组合与一个更大的科学叙事连接起来:长期支持人体的生物韧性。

BGG should not compete only on cost, supply capacity, or ingredient specifications. Those are necessary, but not sufficient. We should compete on scientific interpretation, application innovation, clinical relevance, and long-term trust. The life-clock theory can help BGG develop a more advanced anti-aging platform, connecting our ingredient portfolio with a larger scientific narrative: supporting the body's biological resilience over time.

在实践层面,这意味着 BGG 可以帮助客户围绕更精确的健康寿命概念开发产品:抗疲劳与能量韧性、炎症平衡与恢复、代谢健康与体重管理、微血管循环与运动表现、皮肤和眼部老龄化支持、细胞膜与线粒体保护,以及面向中老年人群的主动健康老龄化。

In practical terms, this means BGG can help customers build products around more precise health-span concepts: anti-fatigue and energy resilience, inflammation balance and recovery, metabolic health and weight management, microvascular circulation and performance, skin and eye aging support, cell membrane and mitochondrial protection, and active aging for older adults.

负责任的前进路径 · A Responsible Path Forward

生物年龄时钟的发展仍在演进中。这些工具具有前景,但不应被视为最终或完美的工具。不同的时钟测量不同的生物学信号。有些时钟具有更强的预测能力,有些可能更适合研究场景,而不一定适合日常消费者测试。行业必须避免过度解读任何单一测量结果。然而,方向已经清晰。

The development of biological-age clocks is still evolving. These tools are promising, but they should not be treated as final or perfect. Different clocks measure different biological signals. Some are more predictive than others. Some may be more useful in research than in everyday consumer testing. The industry must avoid overinterpreting any single measurement. However, the direction is clear.

对于 BGG 而言,这形成了明确的战略要求:我们必须将成分科学、配方设计、临床证据和生物年龄思维整合为一个平台。我们的角色不只是生产天然成分。我们的角色是帮助定义天然成分如何为下一代健康老龄化解决方案作出贡献。

For BGG, this creates a clear strategic mandate: we must integrate ingredient science, formulation design, clinical evidence, and biological-age thinking into one platform. Our role is not only to produce natural ingredients. Our role is to help define how natural ingredients can contribute to the next generation of healthy-aging solutions.

结语 · Conclusion: The Clock Is a Challenge to the Industry

"生命时钟"概念正在推动抗衰老行业变得更加严肃。它要求我们从宣称走向机制,从趋势走向证据,从孤立成分走向生物系统。对于 BGG 而言,这不是威胁,而是机会。我们已经处在与健康老龄化深度相关的品类之中。下一步,是将这些优势纳入一个更严谨的科学框架之中。

The "life clock" concept challenges the anti-aging industry to become more serious. It asks us to move from claims to mechanisms, from trends to evidence, and from isolated ingredients to biological systems. For BGG, this is not a threat. It is an opportunity. We already operate in categories deeply connected to healthy aging. The next step is to organize these strengths under a more rigorous scientific framework.

未来的抗衰老市场,将属于能够清晰回答三个问题的企业:产品作用于哪些生物衰老通路?这些通路如何与功能性健康相关?其效果如何被负责任地衡量?

"The future of anti-aging will belong to companies that can answer three questions clearly: What biological aging pathways does the product address? How are those pathways connected to functional health? And how can the effect be measured responsibly?"
Key Takeaways · 核心要点
  • 生物年龄时钟科学正将抗衰老行业从宣称驱动转向机制驱动。The "life clock" framework is shifting anti-aging from claim-driven to mechanism-driven.
  • BGG 核心成分(虾青素、岩藻黄质、生育三烯酚、苹果多酚)已与多个生物衰老通路高度相关。BGG's core ingredients already operate across multiple biological aging pathways.
  • 负责任的定位语言是生物韧性,而非逆转衰老或延长寿命。The responsible positioning language is biological resilience — not reversing age or extending life.
  • 未来创新应朝三个方向发展:与衰老机制连接、更多人体证据、更有逻辑的配方设计。Future innovation must move toward three directions: mechanistic connection, human evidence, and formulation logic.

李琨(Kun Li) · CEO, BGG Group · BGG Life Vol. 1, No. 1 · June 2026

Costco Protein Aisle, May 2026: Shelf Observation Report and Implications for BGG Ingredient Strategy

2026年5月好市多蛋白质货架现场观察报告及对BGG原料战略的启示

🔒 Internal Only
Context · 背景
Costco Wholesale is the United States' largest warehouse club retailer and one of the most reliable single-channel indicators of mainstream consumer health trends. Products that secure Costco shelf space have typically cleared the bar on price-per-unit value, consumer trust, and volume velocity. An in-store shelf observation of the protein aisle in May 2026 reveals the current competitive landscape in mass-market protein nutrition — and identifies a meaningful white space for functional ingredient differentiation.

Products Observed · 观察到的产品

Brand Product Protein / Serving Pack Size Price
Huel Black EditionRTD Chocolate Shake35 g12-pack
Super Coffee Protein+Caffè Latte Shake25 g15-pack
Fairlife Core PowerChocolate Milk Shake42 g12-pack$24.99
Ascent100% Whey Vanilla Bean25 g / scoop4 lb · 62 servings
LevelsGrass-Fed Whey Vanilla Bean24 g / scoop5.64 lb · 80 servings$59.99
OikosVanilla Protein Shake30 g18-pack
NurriChocolate Ultra-Filtered Milk Shake30 g15-pack$24.90
Premier ProteinChocolate / Café Latte Shake30 g18-pack$31.99

Key Observations · 核心观察

At a Glance · 速览
  • RTD dominates shelf space — 6 of 8 products are ready-to-drink; convenience is the primary purchase driver in this channel.
  • 30 g protein is the category floor — products cluster at 30 g, with Core Power (42 g) and Huel (35 g) commanding premium positioning above it.
  • Chocolate & vanilla only — every visible product is chocolate or vanilla. Classic flavors = bulk-buying sell-through confidence.
  • Plant-based is niche — only Huel offers plant protein (pea + faba bean). All other products are dairy-based.
  • Premier Protein is the category anchor — two SKUs side-by-side, dominant floor presence, highest stacking density.

Price-per-Serving Economics · 每份成本分析

Brand Price Units Protein / Unit $/Serving
Premier Protein$31.9918 RTD30 g~$1.78
Nurri$24.9015 RTD30 g~$1.66
Fairlife Core Power$24.9912 RTD42 g~$2.08
Levels Whey (powder)$59.9980 servings24 g~$0.75

Powders remain the most cost-efficient format at ~$0.75/serving. RTDs command a 2–3× convenience premium, concentrated between $1.66–$2.08/serving. The RTD premium is structural, not incidental — it reflects the channel's core value proposition of grab-and-go nutrition at warehouse scale.

"The Costco protein aisle in 2026 tells one story very clearly: volume, convenience, and dairy dominance. Functional differentiation — antioxidant, anti-inflammatory, metabolic support — is entirely absent. That is the white space."

Strategic Implications for BGG · 对BGG的战略启示

The Costco protein aisle in May 2026 is a high-volume, low-differentiation environment. Every brand competes on protein grams, pack size, and price-per-serving. No product visible in the aisle carries a functional health claim beyond protein content itself — no antioxidant positioning, no anti-inflammatory story, no metabolic health narrative, no ingredient-origin differentiation beyond "grass-fed" or "ultra-filtered milk."

This is precisely where BGG's ingredient portfolio has strategic relevance — not as a direct-to-consumer protein brand, but as a B2B functional ingredient supplier to the better-for-you RTD segment.

The BGG Ingredient Differentiation Opportunity · BGG原料差异化机会

BGG's core algae-derived ingredients address biological functions that are entirely absent from the current Costco protein shelf:

  • AstaZine® (natural astaxanthin) — antioxidant protection, muscle recovery, anti-inflammatory support, and eye health. Directly relevant to the sports recovery RTD segment.
  • ThinOgen® (fucoxanthin) — metabolic health, fat metabolism, body composition support. Relevant to the weight-management protein RTD niche, which Costco does not currently carry at meaningful scale.
  • ApplePhenon® (apple polyphenols) — metabolic resilience, anti-inflammatory signaling, glycemic management. Formulation-compatible with dairy-based RTDs.
  • TheraPrimE® (tocotrienols) — cardiovascular and cognitive health positioning. Differentiated claim story for premium RTD formats.

The most actionable near-term opportunity is the sports recovery RTD segment. Core Power at 42 g protein and $2.08/serving demonstrates that consumers will pay a premium for a product with a differentiated nutritional story. Adding AstaZine® to a high-protein RTD creates a "protein + recovery antioxidant" claim structure that no current Costco product offers — a genuine first-mover positioning at the functional-sports-nutrition intersection.

A secondary opportunity lies in the better-for-you RTD white space. Huel's inclusion at Costco — a plant-based, nutrient-complete meal replacement — suggests the channel is open to non-traditional protein formats that carry a strong health narrative. A co-formulation or co-branding partnership with an emerging RTD brand incorporating BGG algae actives could be positioned in the same "premium functional" tier.

The B2B play is cleaner than a DTC entry. BGG supplies the functional differentiation ingredient; the brand partner handles Costco's strict retail and logistics requirements. For BGG, this represents a channel access strategy without the capital intensity of building consumer brand equity independently.

Key Takeaways · 核心要点
  • Costco's protein aisle is dominated by dairy RTDs at ~30 g protein and $1.66–$2.08/serving — high velocity, low functional differentiation. / 好市多蛋白质货架以乳基即饮产品为主,功能性差异化几乎为零。
  • No product in the observed aisle carries antioxidant, anti-inflammatory, or metabolic health claims — this is the functional white space BGG can address. / 观察到的所有产品均无抗氧化、抗炎或代谢健康声明——这是BGG可以切入的差异化空间。
  • AstaZine® is the most immediately formulation-relevant BGG ingredient for the sports recovery RTD segment given its muscle-recovery and antioxidant mechanism. / 虾青素是BGG在运动恢复即饮产品领域最具即时配方相关性的成分。
  • The strategic entry model is B2B ingredient supply to better-for-you RTD brands — not direct retail. / 战略切入模式为向功能性即饮品牌提供B2B原料供应,而非直接零售。

Source: In-store shelf photography, Costco US, May 2026. Compiled by BGG Life Market Intelligence Desk.

From the Archive · 历史存档

Founder's Voice · Historical Perspective · BGG Heritage
Section Editors: Kun Li · Marketing Team

风雨兼程三十年 · 寻草记

BGG founder botanical journey
律诗 · Classical Regulated Verse · Eight Lines
风雨兼程三十年,踏遍山川觅寿丹。
八角异香驱疫虐,黄蒿奇草护生安。
高原红藻添春色,国老甘和助玉颜。
愿使人人增一岁,菩萨垂慈遂夙缘。
Editorial Note · 注释
This poem, written by BGG's founder to mark thirty years of the company's scientific journey, traces the botanical lineage of BGG's ingredient science in classical regulated verse (lǜshī, 律诗). Four plants serve as markers of the journey. The closing couplet — 愿使人人增一岁,菩萨垂慈遂夙缘 ('May every person gain one more year; may compassion fulfil this long-held wish') — frames BGG's thirty-year mission not in commercial but in human terms: the wish that natural science might extend and enrich human life.
诗中植物 / Botanical原文 / Verse ReferenceBGG科学关联 / BGG Science Connection
八角茴香
Star Anise
Illicium verum
八角异香驱疫虐Traditional antimicrobial applications; shikimic acid source for antiviral research. Represents BGG's roots in traditional Chinese botanical science.
青蒿 / 黄蒿
Sweet Wormwood
Artemisia annua
黄蒿奇草护生安Source of artemisinin — the Nobel Prize-winning antimalarial compound. Represents the power of traditional botanical knowledge to yield world-changing medicine.
雨生红球藻
Haematococcus pluvialis
(AstaZine® source microalgae)
高原红藻添春色BGG's signature ingredient. The highland plateau algae whose astaxanthin content is the foundation of AstaZine® — BGG's most clinically documented and commercially significant ingredient.
甘草 / 国老
Licorice Root
Glycyrrhiza uralensis
国老甘和助玉颜'国老' (Elder of the Nation) is the classical honorific for licorice in Chinese medicine — the harmonising herb. BGG's licorice extract portfolio addresses skin health, immune function, and anti-inflammatory applications.

Mr. Li 李春华 · Founder & CEO, BGG Global · BGG Life Vol. 5, May 2026

样文:BGG与虾青素时代

Sample Article: BGG and the Astaxanthin Era · 占位稿 (Placeholder)

BGG astaxanthin era placeholder
本栏目征稿 · Open Call for Contributions
本栏目将由长期服务于BGG的全体成员撰写个人感想及历史回顾文章。欢迎联系:bgglife@bggworld.com

To be replaced by a commissioned historical or personal piece from a long-tenured BGG team member. Contact: bgglife@bggworld.com

每一家伟大的企业,都始于一个关键洞察——一个发现、一项技术,或一种物质,并围绕其逐步构建起完整的科学体系与商业生态。对于BGG而言,这一奠基性的洞察,正是虾青素(Astaxanthin)。

Every company has a founding insight — a moment, a technology, or a substance around which an entire scientific and commercial architecture is built. For BGG, that founding insight is astaxanthin.

虾青素是一种天然类胡萝卜素色素,广泛存在于微藻、海洋生物以及部分细菌之中。作为自然界已知抗氧化能力最强的天然活性物质之一,它长期吸引着科学界对于健康老龄化、运动恢复、认知功能以及代谢健康等领域的研究关注。

Astaxanthin is a carotenoid pigment found in microalgae, marine animals, and certain bacteria. It possesses one of the highest antioxidant capacities among naturally occurring compounds and has attracted decades of scientific interest in healthy ageing, exercise recovery, cognitive function, and metabolic health.

然而,真正让虾青素从实验室走向全球市场的,并不仅仅是科学发现本身。更重要的是,一群科学家、工程师与企业经营者持续数十年的坚持与投入。BGG如何突破微藻规模化培养技术瓶颈,如何建立高品质提取工艺体系,如何通过长期临床研究不断积累科学证据——这些都构成了BGG发展历史中最值得被完整记录的重要篇章。

The story of how BGG overcame cultivation challenges, developed extraction technologies, validated product stability, and patiently accumulated clinical evidence deserves to be told in full. This space is reserved for a scientist or leader who personally participated in BGG's astaxanthin journey and can tell the story in their own voice.

📧 bgglife@bggworld.com

《BGG Life》· Masthead · 刊头信息

Vol. 1 · No. 1
June 2026 · 2026年6月

李琨(Kun Li)
BGG Global 集团总经理(CEO)

张扬 博士
丁立新 博士
关川 博士

刘雨馨
Caroline Schroeder
Thomas Adler

孙经纬

于叶露

董事会成员(Board Members)
李春华
李艳梅
Bharat R.

BGG Life Editorial Production Agent v3.0

BGG Group
www.bggworld.com.cn
www.bggworld.com

发行声明 · Distribution Notice

《BGG Life》为BGG全球团队内部月刊,仅供内部交流与知识共享使用。带有 🔒 INTERNAL ONLY 标识的文章包含商业敏感信息,未经授权不得向外部传播、转发或引用。

BGG Life is published monthly for members of the BGG Global organisation and is intended solely for internal communication and knowledge sharing. Articles marked 🔒 INTERNAL ONLY contain confidential commercial information and must not be shared, forwarded, or quoted outside the organisation without Editorial team approval.

刊物内容尽限内部传阅,未经总编团队审核、许可不得在任何公众媒体、渠道公开。
"理解历史,是创造未来的开始。"
"Understanding history is the beginning of creating the future."